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Insta-Char and Sotalol

Determining the interaction of Insta-Char and Sotalol and the possibility of their joint administration.

Check result:
Insta-Char <> Sotalol
Relevance: 05.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using sotalol together with charcoal. Using these medications together can make sotalol less effective. Do not take charcoal with any other medication. Charcoal binds to other drugs and reduces their effectiveness, which could become dangerous. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Charcoal reduces the absorption of sotalol by 99% and effectively shortens its elimination half-life. Subtherapeutic levels will result.

MANAGEMENT: While charcoal is an effective antidote for sotalol overdose, its use as a remedy for GI symptoms should be avoided by patients taking sotalol.

References
  • Karkkainen S, Neuvonen PJ "Effect of oral charcoal and urine pH on sotalol pharmacokinetics." Int J Clin Pharmacol Ther Toxicol 22 (1984): 441-6
Insta-Char

Generic Name: charcoal

Brand name: Actidose-Aqua, Activated Charcoal, Charcoal Plus DS, EZChar, Insta-Char, Liqui-Char, Optimum Charcoal, Liqui-Char with Sorbitol, Charcocaps, Activated Charcoal with Sorbitol, Charcoaid 2000, Charcoaid-G, Char-Flo with Sorbitol, Charcoaid, Charcodote, Char-Flo Aqueous Base, Actidose-Aqua Advance, JL. Bragg's Medicinal Charcoal, Medicoal, Karbons, Carbomix, Carbosorb X, Charcotabs, Healthstream Activated Charcoal, Charcotrace, Chem Mart Nasal Decongestant Capsule, Pharmacia Carbosorb, Norit, Eucarbon, Active Carbon

Synonyms: n.a.

Sotalol

Generic Name: sotalol

Brand name: Betapace, Betapace AF, Sorine, Sotalol Hydrochloride AF, Sotylize

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction