Insulin (Oral Inhalation) and Tobi
Determining the interaction of Insulin (Oral Inhalation) and Tobi and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using insulin inhalation, rapid acting together with other inhaled products such as tobramycin may affect the absorption of insulin into the blood stream. This may alter the effectiveness of the insulin. Consistent timing of dosing of other inhaled products relative to insulin inhalation, rapid acting is recommended, and blood glucose should be closely monitored. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Bronchodilators and other orally inhaled products may alter the absorption of inhaled human insulin. In nondiabetic subjects with mild asthma (n=36) and moderate asthma (n=31), administration of albuterol 30 minutes prior to inhaled human insulin resulted in a mean increase in insulin systemic exposure (AUC) and peak plasma concentration (Cmax) of 25% to 50% compared to administration of inhaled human insulin alone.
MANAGEMENT: Consistent timing of dosing of other inhaled products relative to inhaled human insulin administration is recommended. Blood glucose should be monitored closely, and the insulin dose adjusted accordingly.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: insulin inhalation, rapid acting
Brand name: Afrezza, Exubera, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, Afrezza 4 unit- 8 unit, Afrezza 8 unit- 12 unit, Afrezza Titration Pack, Exubera
Synonyms: Insulin (inhalation)
Generic Name: tobramycin
Brand name: Bethkis, Kitabis Pak, Tobi, TOBI Podhaler
Synonyms: Tobi (inhalation)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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