Intelence and Leuprolide and norethindrone Intramuscular, Oral
Determining the interaction of Intelence and Leuprolide and norethindrone Intramuscular, Oral and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with etravirine may slightly increase the plasma concentrations of ethinyl estradiol. The mechanism of interaction has not been described. In 16 study subjects administered ethinyl estradiol-norethindrone (35 mcg-1 mg) once a day with etravirine, ethinyl estradiol peak plasma concentration (Cmax), systemic exposure (AUC) and trough plasma concentration (Cmin) increased by 33%, 22% and 9%, respectively. These changes were statistically, but not clinically, significant. Etravirine had no effect on the pharmacokinetics of norethindrone. Etravirine and ethinyl estradiol-norethindrone may be coadministered without any dosage adjustments. No data are available for other estrogen or progestin products.
- "Product Information. Intelence (etravirine)." Ortho Biotech Inc, Bridgewater, NJ.
Generic Name: leuprolide / norethindrone
Brand name: Lupaneta Pack
Synonyms: Leuprolide and norethindrone, Leuprolide and Norethindrone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Intelence-Leuprolide Injection (CPP)
- Intelence-Leuprolide Injection (Prostate)
- Intelence-Leuprolide Injection (Women)
- Intelence-Leuprolide Intramuscular, Subcutaneous, Intradermal, Injection
- Intelence-Leustatin
- Intelence-Leustatin injection
- Leuprolide and norethindrone Intramuscular, Oral-Interferon alfa-2b
- Leuprolide and norethindrone Intramuscular, Oral-Interferon alfa-2b Injection
- Leuprolide and norethindrone Intramuscular, Oral-Interferon Alfa-2b Injection Solution
- Leuprolide and norethindrone Intramuscular, Oral-Interferon Alfa-2b Powder for Injection
- Leuprolide and norethindrone Intramuscular, Oral-Interferon Alfa-2b Prefilled Pens
- Leuprolide and norethindrone Intramuscular, Oral-Interferon alfa-n3