Intelence and Norpace CR

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using etravirine together with disopyramide may decrease the effects of disopyramide. Contact your doctor if your condition changes or if you experience a worsening of heart symptoms If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration with etravirine may decrease the plasma concentrations of certain antiarrhythmic agents. The proposed mechanism is etravirine induction of CYP450 3A4, the isoenzyme responsible for the metabolic clearance of antiarrhythmics such as amiodarone, bepridil, disopyramide, lidocaine, and quinidine.

MANAGEMENT: Caution is advised if etravirine is prescribed to patients receiving antiarrhythmic agents. Drug concentration monitoring is recommended, if available.

Intelence

Generic Name: etravirine

Brand name: Intelence

Synonyms: n.a.

What is Intelence?

Norpace CR

Generic Name: disopyramide

Brand name: Norpace, Norpace CR

Synonyms: n.a.

What is Norpace CR?