Ioflupane I-123 and Promethazine and Phenylephrine
Determining the interaction of Ioflupane I-123 and Promethazine and Phenylephrine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Promethazine may interfere with imaging studies done with ioflupane I-123. Let your doctor know you are receiving or have recently received promethazine if you are scheduled for an imaging diagnostic procedure with ioflupane I-123. You may need to stop using promethazine for a certain amount of time before having the procedure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Theoretically, dopamine agonists (e.g., antiparkinson agents, ergot derivatives) and antagonists (e.g., neuroleptics, antiemetics) may affect imaging results obtained using ioflupane I-123, which binds to the dopamine transporter. However, their concomitant use has not been extensively studied. Whether discontinuation of these drugs prior to ioflupane I-123 administration may help to minimize potential interference is unknown.
MANAGEMENT: Clinicians using ioflupane I-123 should be aware of possible diagnostic interference by dopamine agonists and antagonists.
- "Product Information. DaTscan (ioflupane I-123)." GE Healthcare, Princeton, NJ.
Generic Name: ioflupane I 123
Brand name: DaTscan
Synonyms: Ioflupane I 123
Generic Name: phenylephrine / promethazine
Brand name: Phenergan VC, Promethazine VC Plain, Promethazine VC
Synonyms: Phenylephrine and promethazine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ioflupane I-123-Promethazine Hydrochloride
- Ioflupane I-123-Promethazine injection
- Ioflupane I-123-Promethazine Injection, Intravenous
- Ioflupane I-123-Promethazine rectal
- Ioflupane I-123-Promethazine Suppositories
- Ioflupane I-123-Promethazine Syrup
- Promethazine and Phenylephrine-Iohexol
- Promethazine and Phenylephrine-Iohexol Injection, Oral, Rectal
- Promethazine and Phenylephrine-Ionamin
- Promethazine and Phenylephrine-Ionil Plus
- Promethazine and Phenylephrine-Ionil Plus Topical
- Promethazine and Phenylephrine-Ionil T