IPlex and Simcor

• Generic Name: mecasermin rinfabate
• Dosage Forms: n.a.
• Other Brand Names: IPlex

iPlex is a man-made form of insulin-like growth factor-1 (IGF-1), which is normally produced by the body. IGF-1 is important for the growth of bones and muscles.

iPlex is used to treat growth failure in children whose bodies do not make enough IGF-1.

iPlex may also be used for other purposes not listed in this medication guide.

• Generic Name: niacin / simvastatin
• Dosage Forms: tablet, film coated, extended release
• Other Brand Names: Simcor

Simcor contains a combination of niacin and simvastatin.

Simcor is used to lower cholesterol and triglycerides (types of fat) in the blood. Simcor is used along with diet to lower levels of total cholesterol, LDL "bad" cholesterol, and triglycerides and to increase HDL "good" cholesterol.

Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. Niacin is also present in many multiple vitamins and nutritional supplements.

Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).

Simcor may also be used for purposes not listed in this medication guide.