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Irinotecan (Conventional) and Prochlorperazine

Determining the interaction of Irinotecan (Conventional) and Prochlorperazine and the possibility of their joint administration.

Check result:
Irinotecan (Conventional) <> Prochlorperazine
Relevance: 22.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

In clinical trials, the incidence of akathisia was greater when prochlorperazine was administered on the same day (8.5%) than when these drugs were administered on separate days (1.3%).

References
  • "Product Information. Camptosar (irinotecan)." Pharmacia and Upjohn, Kalamazoo, MI.
Irinotecan (Conventional)

Generic Name: irinotecan

Brand name: Camptosar

Synonyms: Irinotecan

Prochlorperazine

Generic Name: prochlorperazine

Brand name: Compazine, Compro

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle