Irinotecan Hydrochloride and Pharmorubicin Pfs

• Generic Name: irinotecan
• Dosage Forms: n.a.
• Other Brand Names: Camptosar

Conventional irinotecan: Used as a component of first-line therapy in combination with fluorouracil and leucovorin for the treatment of metastatic carcinoma of the colon or rectum.

Conventional irinotecan: Used as a single agent for treatment of metastatic carcinoma of the colon or rectum in patients whose disease has recurred or progressed following initial therapy with fluorouracil-based antineoplastic regimens.

Liposomal irinotecan: Used in combination with fluorouracil and leucovorin for the treatment of metastatic adenocarcinoma of the pancreas in patients whose disease has progressed following gemcitabine-based chemotherapy (designated an orphan drug by FDA for treatment of this cancer ).

Conventional irinotecan: Used in combination with cisplatin for the initial treatment of extensive small cell lung cancer.

Conventional irinotecan: Under investigation for the treatment of metastatic or recurrent cervical cancer.

• Generic Name: epirubicin
• Dosage Forms: n.a.
• Other Brand Names: Ellence, Pharmorubicin Pfs, Pharmorubicin RDF

Epirubicin injection is used together with other cancer medicines to treat cancers of the breast, lungs, lymph system, stomach, and ovaries.

Epirubicin belongs to the group of medicines called antineoplastics. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used.

This medicine is to be administered only by or under the immediate supervision of your doctor.