Irinotecan Hydrochloride and Sublocade

• Generic Name: irinotecan
• Dosage Forms: n.a.
• Other Brand Names: Camptosar

Conventional irinotecan: Used as a component of first-line therapy in combination with fluorouracil and leucovorin for the treatment of metastatic carcinoma of the colon or rectum.

Conventional irinotecan: Used as a single agent for treatment of metastatic carcinoma of the colon or rectum in patients whose disease has recurred or progressed following initial therapy with fluorouracil-based antineoplastic regimens.

Liposomal irinotecan: Used in combination with fluorouracil and leucovorin for the treatment of metastatic adenocarcinoma of the pancreas in patients whose disease has progressed following gemcitabine-based chemotherapy (designated an orphan drug by FDA for treatment of this cancer ).

Conventional irinotecan: Used in combination with cisplatin for the initial treatment of extensive small cell lung cancer.

Conventional irinotecan: Under investigation for the treatment of metastatic or recurrent cervical cancer.

• Generic Name: buprenorphine
• Dosage Forms: subcutaneous injection
• Other Brand Names: Sublocade, Belbuca, Buprenex, Probuphine, Butrans, Subutex

Sublocade (buprenorphine) is an opioid medication, sometimes called a narcotic.

Sublocade is used to treat opioid addiction. It is not for use as a pain medication.

Sublocade is given to people who have started addiction treatment with an oral form of buprenorphine placed under the tongue or inside the cheek (such as Suboxone or Subutex).

Sublocade is available only in a certified healthcare setting under a special program. You will not be able to give yourself this medicine.