Irinotecan Intravenous and Sodium Picosulfate, Magnesium Oxide, and Citric Acid Solution
Determining the interaction of Irinotecan Intravenous and Sodium Picosulfate, Magnesium Oxide, and Citric Acid Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:If you are currently receiving treatment with irinotecan, let your doctor know before you use any kind of medication that has a laxative effect. Because irinotecan causes diarrhea in the majority of patients, it may not be advisable for you to use laxatives or bowel cleansing products, as this may increase the risk of dehydration and electrolyte abnormalities. In severe cases, dehydration and electrolyte abnormalities can lead to irregular heart rhythm, seizures, and kidney problems. Contact your doctor if you experience potential signs and symptoms of fluid and electrolyte depletion such as dizziness, lightheadedness, dry mouth, thirst, fatigue, weakness, muscle cramps, decreased urination, palpitation, and increased heart rate. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Because irinotecan has been reported to cause diarrhea in the majority of treated patients, the use of laxatives may not be appropriate during irinotecan therapy.
MANAGEMENT: In patients requiring laxatives for constipation associated with narcotic administration, the standard regimen may be continued under supervision of the clinician. However, patients should be advised to inform their physician of any changes in their bowel habit so that dosage adjustments or discontinuation of laxatives may be done promptly.
- "Product Information. Camptosar (irinotecan)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: irinotecan
Brand name: Camptosar
Synonyms: Irinotecan, Irinotecan (Conventional)
Generic Name: citric acid / magnesium oxide / sodium picosulfate
Brand name: Clenpiq, Prepopik
Synonyms: Citric acid, magnesium oxide, and sodium picosulfate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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