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Irinotecan liposomal and Pancuronium

Determining the interaction of Irinotecan liposomal and Pancuronium and the possibility of their joint administration.

Check result:
Irinotecan liposomal <> Pancuronium
Relevance: 26.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Theoretically, irinotecan may antagonize the pharmacologic effect of nondepolarizing neuromuscular blocking agents due to its anticholinesterase activity, resulting in increased dosage requirements for adequate skeletal muscle relaxation. However, the interaction has not been studied or reported in a clinical setting.

References
  • "Product Information. Camptosar (irinotecan)." Pharmacia and Upjohn, Kalamazoo, MI.
Irinotecan liposomal

Generic Name: irinotecan liposomal

Brand name: Onivyde

Synonyms: Irinotecan (Liposomal)

Pancuronium

Generic Name: pancuronium

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction