Irinotecan liposome Intravenous and Laronidase

• Generic Name: irinotecan liposomal
• Dosage Forms: n.a.
• Other Brand Names: Onivyde

Irinotecan liposome injection is given along with other medicines to treat metastatic cancer (a cancer that has already spread) of the pancreas in patients who have received gemcitabine.

Irinotecan liposome belongs to the group of medicines called antineoplastics (cancer medicines). It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious, but may cause concern. Some effects may occur after treatment with irinotecan liposome has been stopped. Be sure that you have discussed with your doctor the possible side effects of irinotecan liposome as well as the good it can do.

Irinotecan liposome is available only with your doctor's prescription.

• Generic Name: laronidase
• Dosage Forms: n.a.
• Other Brand Names: Aldurazyme

Laronidase contains an enzyme that occurs naturally in the body in healthy people. Some people lack this enzyme because of a genetic disorder. Laronidase helps replace this missing enzyme in such people.

Laronidase is used to treat some of the symptoms of a genetic condition called mucopolysaccharidosis (MYOO-koe-pol-ee-SAK-a-rye-DOE-sis) or MPS I, also called Hurler syndrome, Hurler-Scheie syndrome, or Scheie syndrome.

MPS I is a metabolic disorder in which the body lacks the enzyme needed to break down certain substances. These substances can build up in the body, causing enlarged organs, abnormal bone structure, changes in facial features, breathing problems, heart problems, vision or hearing loss, and changes in mental or physical abilities.

Laronidase may improve breathing and walking ability in people with this condition. However, this medication is not a cure for MPS I.

Laronidase may also be used for purposes not listed in this medication guide.