Irinotecan liposome Intravenous and Quelicin
Determining the interaction of Irinotecan liposome Intravenous and Quelicin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Theoretically, irinotecan may augment the pharmacologic effect of depolarizing neuromuscular blocking agents due to its anticholinesterase activity. Depolarizing neuromuscular blocking agents are rapidly hydrolyzed by plasma cholinesterase, thus inhibitors of cholinesterase may reduce their clearance from plasma and prolong their effect. However, the interaction has not been studied or reported in a clinical setting.
- "Product Information. Anectine (succinylcholine)." Glaxo Wellcome, Research Triangle Park, NC.
- "Product Information. Camptosar (irinotecan)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: irinotecan liposomal
Brand name: Onivyde
Synonyms: Irinotecan liposomal, Irinotecan (Liposomal)
Generic Name: succinylcholine
Brand name: Anectine, Quelicin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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