Iron Chews Pediatric and Lanthanum Carbonate Tablets
Determining the interaction of Iron Chews Pediatric and Lanthanum Carbonate Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Lanthanum carbonate and carbonyl iron should not be taken orally at the same time. These medications may interfere with each other's absorption into the bloodstream, which may reduce the effects of both medications. To minimize the potential for interaction, avoid taking carbonyl iron within 2 hours of taking lanthanum carbonate. Talk to a healthcare professional if you have questions on how to take these or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Theoretically, lanthanum carbonate may chelate with certain drugs in the gastrointestinal tract, resulting in reduced oral bioavailability of those drugs during coadministration. However, an in vitro study involving digoxin, enalapril, furosemide, metoprolol, phenytoin, and warfarin found no evidence that lanthanum carbonate forms insoluble complexes with these drugs in simulated gastric fluid. Studies in healthy subjects have also found no effect of lanthanum carbonate (1000 mg for 4 doses) on the absorption of a single dose of digoxin (0.5 mg), metoprolol (100 mg), or warfarin (10 mg).
MANAGEMENT: To minimize the potential for interaction, drugs that are known to interact with antacids (e.g., ACE inhibitors, beta blockers, bisphosphonates, coumarin derivatives, digitalis glycosides, fluoroquinolones, iron, phenytoin, rifampin, tetracyclines, thyroid preparations, valproic acid) should not be taken within 2 hours of administration of lanthanum carbonate according to the product labeling.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
- "Product Information. Seysara (sarecycline)." Allergan Inc, Irvine, CA.
- "Product Information. Fosrenol (lanthanum carbonate)." Shire US Inc, Florence, KY.
- "Product Information. Nuzyra (omadacycline)." Paratek Pharmaceuticals, Inc., Boston, MA.
- Cerner Multum, Inc. "Australian Product Information." O 0
Generic Name: carbonyl iron
Brand name: Iron Chews Pediatric, Feosol Caplet, Icar, Iron Chews, Wee Care, Ferra-Cap, Elemental Iron
Synonyms: n.a.
Generic Name: lanthanum carbonate
Brand name: Fosrenol
Synonyms: Lanthanum carbonate, Lanthanum
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Iron Chews Pediatric-Lanthanum Chewable Tablets
- Iron Chews Pediatric-Lanthanum Powder
- Iron Chews Pediatric-Lantus
- Iron Chews Pediatric-Lantus SoloStar
- Iron Chews Pediatric-Lantus SoloStar (Insulin Glargine (U-100) Cartridge Systems and Pens)
- Iron Chews Pediatric-Lantus Solostar (Insulin Glargine (U-300) Pens)
- Lanthanum Carbonate Tablets-Iron Complex
- Lanthanum Carbonate Tablets-Iron dextran
- Lanthanum Carbonate Tablets-Iron Dextran Complex
- Lanthanum Carbonate Tablets-Iron dextran Injection
- Lanthanum Carbonate Tablets-Iron Hydrogenated Dextran
- Lanthanum Carbonate Tablets-Iron polysaccharide