Ismelin and Stalevo

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Limited data from two patients suggest that the antihypertensive effects of guanethidine are enhanced by the addition of levodopa. The mechanism is unknown. Because of the paucity of data, it is not clear if an interaction exists. If guanethidine and levodopa are used concomitantly, monitoring of blood pressure is recommended, especially orthostatic measurements. Also, the clinician should be aware that if levodopa is discontinued, the antihypertensive effects of guanethidine could be decreased.

Ismelin

Generic Name: guanethidine

Brand name:

Synonyms: Ismelin (Oral)

What is Ismelin?

Stalevo

Generic Name: carbidopa / entacapone / levodopa

Brand name: Stalevo, Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75

Synonyms: n.a.

What is Stalevo?