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Isoflurane and Ritalin LA

Determining the interaction of Isoflurane and Ritalin LA and the possibility of their joint administration.

Check result:
Isoflurane <> Ritalin LA
Relevance: 08.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

If you are currently being treated with methylphenidate, you should talk to your doctor before undergoing surgery where isoflurane may be used. Combining these medications may increase the risk of high blood pressure and irregular heart beat during surgery. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The administration of volatile general anesthetics during methylphenidate therapy may increase the risk of hypertension and/or arrhythmias during surgery. The proposed mechanism is anesthetic-induced myocardial sensitization to the stimulation caused by methylphenidate.

MANAGEMENT: When surgery is planned, it is recommended that methylphenidate should not be taken on the day of surgery.

References
  • "Product Information. Metadate CD Capsules (methylphenidate)" Celltech Pharmaceuticals, Inc, Applegate, WI.
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Cerner Multum, Inc. "Australian Product Information." O 0
Isoflurane

Generic Name: isoflurane

Brand name: Forane, Terrell

Synonyms: n.a.

Ritalin LA

Generic Name: methylphenidate

Brand name: Adhansia XR, Aptensio XR, Concerta, Cotempla XR-ODT, Jornay PM, Metadate ER, Methylin, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA, Metadate CD, Ritalin SR, Daytrana, Methylin ER

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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