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Isometheptene, Caffeine, and Acetaminophen Tablets and Reglan

Determining the interaction of Isometheptene, Caffeine, and Acetaminophen Tablets and Reglan and the possibility of their joint administration.

Check result:

Isometheptene, Caffeine, and Acetaminophen Tablets <> Reglan

Relevance: 01.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with metoclopramide may enhance the rate and extent of absorption of drugs that are mainly absorbed in the small intestine, such as paracetamol, aspirin, and tetracycline. The proposed mechanism is a metoclopramide-mediated increase in gastric emptying. Clinical and laboratory monitoring should be considered and the dose adjusted as appropriate. The clinical significance of this interaction is unknown.

References

Cerner Multum, Inc. "Australian Product Information." O 0
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Nimmo J, Heading RC, Tothill P, Prescott LF "Pharmacological modification of gastric emptying: effects of propantheline and metoclopramide on paracetamol absorption." Br Med J 1 (1973): 587-9
"Product Information. Reglan (metoclopramide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.

Isometheptene, Caffeine, and Acetaminophen Tablets

Generic Name: acetaminophen / caffeine / isometheptene mucate

Brand name: Prodrin, MigraTen

Synonyms: Acetaminophen, Caffeine, and Isometheptene Mucate

What is Isometheptene, Caffeine, and Acetaminophen Tablets?

Reglan

Generic Name: metoclopramide

Brand name: Reglan, Metozolv ODT

Synonyms: n.a.

What is Reglan?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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