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Isoniazid and Sucralfate Oral Suspension

Determining the interaction of Isoniazid and Sucralfate Oral Suspension and the possibility of their joint administration.

Check result:

Isoniazid <> Sucralfate Oral Suspension

Relevance: 10.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Aluminum salts may slightly decrease the absorption of isoniazid. The mechanism is not known. To prevent this interaction, isoniazid should be administered one to two hours before administration of an aluminum-containing product.

References

Hurwitz A, Schlozman DL "Effects of antacids on gastrointestional absorption of isoniazid in rat and man." Am Rev Respir Dis 109 (1974): 41-7
Hava M, Hurwitz A "The relaxing effect of aluminum and lanthanum on rat and human gastric smooth muscle in vitro." Eur J Pharmacol 156 (1973): 156-61

Isoniazid

Generic Name: isoniazid

Brand name: Nydrazid

Synonyms: n.a.

What is Isoniazid?

Sucralfate Oral Suspension

Generic Name: sucralfate

Brand name: Carafate

Synonyms: Sucralfate

What is Sucralfate Oral Suspension?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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