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Isoniazid Oral, Intramuscular and Mysoline

Determining the interaction of Isoniazid Oral, Intramuscular and Mysoline and the possibility of their joint administration.

Check result:

Isoniazid Oral, Intramuscular <> Mysoline

Relevance: 11.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Primidone serum concentrations may be increased in patients taking concomitant isoniazid. The mechanism and clinical significance of this interaction are known. If elevated serum primidone levels are observed, this interaction should be suspected, and the primidone dosage may need to be decreased accordingly.

References

Sutton G, Kupferberg HJ "Isoniazid as an inhibitor of primidone metabolism." Neurology 25 (1975): 1179-81

Isoniazid Oral, Intramuscular

Generic Name: isoniazid

Brand name: Nydrazid

Synonyms: Isoniazid

What is Isoniazid Oral, Intramuscular?

Mysoline

Generic Name: primidone

Brand name: Mysoline

Synonyms: n.a.

What is Mysoline?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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