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Isoniazid Solution and Navane Oral

Determining the interaction of Isoniazid Solution and Navane Oral and the possibility of their joint administration.

Check result:
Isoniazid Solution <> Navane Oral
Relevance: 06.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Isoniazid may inhibit the oxidative metabolism of thioxanthenes. Thioxanthene effect may be increased. The clinical significance is unknown.

References
  • Ereshefsky L, Saklad SR, Watanabe MD, Davis CM, Jann MW "Thiothixene pharmacokinetic interactions: a study of hepatic enzyme inducers, clearance inhibitors, and demographic variables." J Clin Psychopharmacol 11 (1991): 296-301
Isoniazid Solution

Generic Name: isoniazid

Brand name: Nydrazid

Synonyms: Isoniazid

Navane Oral

Generic Name: thiothixene

Brand name: Navane

Synonyms: Navane

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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