Isoniazid Syrup and Safinamide Mesylate
Determining the interaction of Isoniazid Syrup and Safinamide Mesylate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using safinamide together with isoniazid may increase the risk of a hypertensive crisis, which is a life-threatening side effect associated with dangerously high blood pressure. Your doctor may be able to prescribe alternatives that do not interact, or you may need more frequent monitoring to safely use both medications. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Isoniazid has some monoamine oxidase inhibiting activity and may have additive pharmacologic effects with other monoamine oxidase inhibitors (MAOIs), including safinamide. Theoretically, coadministration may increase the risk of a hypertensive crisis.
MANAGEMENT: Caution is advised if isoniazid is used concomitantly with safinamide. Clinical and laboratory monitoring, including blood pressure monitoring, should be considered when these drugs are used concomitantly.
- "Product Information. Xadago (safinamide)." US WorldMeds LLC, Louisville , KY.
Generic Name: isoniazid
Brand name: Nydrazid
Synonyms: Isoniazid
Generic Name: safinamide
Brand name: Xadago
Synonyms: Safinamide
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Isoniazid Syrup-Safyral
- Isoniazid Syrup-Saizen
- Isoniazid Syrup-Saizen Subcutaneous, Injection
- Isoniazid Syrup-Sal-Acid Plaster Topical
- Isoniazid Syrup-Sal-Plant
- Isoniazid Syrup-Sal-Plant Gel Topical
- Safinamide Mesylate-Isoniazid Tablets
- Safinamide Mesylate-Isoniazid, pyrazinamide, and rifampin
- Safinamide Mesylate-Isoproterenol
- Safinamide Mesylate-Isoproterenol Hydrochloride
- Safinamide Mesylate-Isoproterenol Injection
- Safinamide Mesylate-Isoptin SR