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Isoproterenol and Twinject

Determining the interaction of Isoproterenol and Twinject and the possibility of their joint administration.

Check result:
Isoproterenol <> Twinject
Relevance: 11.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using isoproterenol together with EPINEPHrine may have additive effects on the heart and cause increased heart rate and blood pressure. Your doctor may need to monitor you closely and possibly take extra precautions for you to safely use these medications together. Consult with your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: The simultaneous administration of parenteral isoproterenol and epinephrine may have additive cardiac stimulant effects and increase the risk of cardiac arrhythmias.

MANAGEMENT: Parenteral isoproterenol and epinephrine should not be administered simultaneously but may be administered alternately after allowing an appropriate interval between doses.

References
  • "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
  • Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
Isoproterenol

Generic Name: isoproterenol

Brand name: Isuprel

Synonyms: n.a.

Twinject

Generic Name: epinephrine

Brand name: EpiPen, Symjepi, Twinject, Adrenalin, Auvi-Q, Epinephrinesnap-EMS, EpiPen 2-Pak, EpiPen JR 2-Pak, EPIsnap, Auvi-Q Auto-injector, Primatene Mist Inhaler, Adrenaclick, Primatene Mist

Synonyms: Twinject Auto-Injector

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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