Isoproterenol Hydrochloride and Tambocor
Determining the interaction of Isoproterenol Hydrochloride and Tambocor and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using flecainide together with isoproterenol can affect the rhythm of your heart. Call your doctor if you have symptoms of irregular heartbeat, chest tightness, blurred vision or nausea. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Flecainide suppression of anterograde conduction through an accessory AV pathway was reversed after an isoproterenol infusion, according to one case report. The proposed mechanism is counteractive pharmacologic effects on the AV-conductive tissue. Patients who have underlying arrhythmias may suffer recurrent or new arrhythmias when isoproterenol is added to their medical regimens, even if antiarrhythmic therapy was previously adequate.
MANAGEMENT: Patients should be monitored for altered antiarrhythmic efficacy during concurrent administration.
- Brembilla-Perrot B, Admant P, Le Helloco A, Pernot C "Loss of efficacy of flecainide in the Wolff-Parkinson-White syndrome after isoproterenol administration." Eur Heart J 6 (1985): 1074-8
Generic Name: isoproterenol
Brand name: Isuprel
Synonyms: Isoproterenol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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