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Isopto Carbachol and Mivacurium

Determining the interaction of Isopto Carbachol and Mivacurium and the possibility of their joint administration.

Check result:
Isopto Carbachol <> Mivacurium
Relevance: 01.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using mivacurium together with carbachol ophthalmic can interfere with the effects of mivacurium. You should be closely monitored for adequate treatment results with mivacurium. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Carbachol antagonizes the action of nondepolarizing neuromuscular blocking agents due to antagonistic effects at the neuromuscular junction in skeletal muscle.

MANAGEMENT: The patient should be monitored for adequate neuromuscular blockade and the dosage adjusted, if necessary.

References
  • Benjamin KW "Toxicity of ocular medications." Int Ophthalmol Clin 19 (1979): 199-255
  • Hardman JG, Limbird LE, Gilman AG, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 10th ed." New York, NY: McGraw-Hill (2001):
Isopto Carbachol

Generic Name: carbachol ophthalmic

Brand name: Isopto Carbachol, Miostat, Carboptic, Carbastat

Synonyms: n.a.

Mivacurium

Generic Name: mivacurium

Brand name: Mivacron

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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