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Isopto Carbachol Ophthalmic Solution and Quelicin

Determining the interaction of Isopto Carbachol Ophthalmic Solution and Quelicin and the possibility of their joint administration.

Check result:

Isopto Carbachol Ophthalmic Solution <> Quelicin

Relevance: 10.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using succinylcholine together with carbachol ophthalmic can prolong the effects of succinylcholine. You should be closely monitored for prolong breathing cessation and muscle weakness after use of carbachol ophthalmic. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Carbachol may prolong and enhance the action of depolarizing neuromuscular blocking agents due to synergistic effects at the neuromuscular junction in skeletal muscle. Patients may experience prolonged muscle weakness and apnea.

MANAGEMENT: Close observation for profound and prolonged respiratory depression and muscle weakness is recommended if these drugs must be used together.

References

Hardman JG, Limbird LE, Gilman AG, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 10th ed." New York, NY: McGraw-Hill (2001):
Benjamin KW "Toxicity of ocular medications." Int Ophthalmol Clin 19 (1979): 199-255

Isopto Carbachol Ophthalmic Solution

Generic Name: carbachol ophthalmic

Brand name: Isopto Carbachol, Miostat, Carboptic, Carbastat

Synonyms: Carbachol ophthalmic, Carbachol

What is Isopto Carbachol Ophthalmic Solution?

Quelicin

Generic Name: succinylcholine

Brand name: Anectine, Quelicin

Synonyms: n.a.

What is Quelicin?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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