Isosorbide dinitrate and Zegerid
Determining the interaction of Isosorbide dinitrate and Zegerid and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Omeprazole may inhibit the drug delivery of oral nitrates. Antianginal effects may be diminished, and myocardial ischemia may be exacerbated. If an interaction is suspected, alternate acid-suppressant therapy may be considered.
- Kajinami K, Mabuchi H "Omeprazole and diminished antianginal drug delivery." Ann Intern Med 121 (1994): 385-6
Generic Name: isosorbide dinitrate
Brand name: Dilatrate-SR, Isochron, Isordil, Sorbitrate, Isordil Titradose, ISDN, Isordil Tembids
Synonyms: Isosorbide Dinitrate
Generic Name: omeprazole / sodium bicarbonate
Brand name: Zegerid, Zegerid OTC
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Isosorbide dinitrate-Zegerid (Omeprazole and Sodium Bicarbonate Capsules)
- Isosorbide dinitrate-Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)
- Isosorbide dinitrate-Zegerid OTC
- Isosorbide dinitrate-Zejula
- Isosorbide dinitrate-Zelapar
- Isosorbide dinitrate-Zelapar Oral
- Zegerid-Isosorbide Dinitrate and Hydralazine
- Zegerid-Isosorbide Dinitrate Extended-Release Capsules and Tablets
- Zegerid-Isosorbide dinitrate Oral, Sublingual
- Zegerid-Isosorbide Dinitrate Tablets
- Zegerid-Isosorbide mononitrate
- Zegerid-Isosorbide Mononitrate Extended Release