Ixabepilone and Xeloda

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

In patients with cancer who received ixabepilone (40 mg/m2) in combination with capecitabine (1000 mg/m2), peak plasma concentration (Cmax) of ixabepilone and capecitabine decreased by 19% and 27%, respectively, compared to administration separately. The interaction is not considered clinically significant given that the combination therapy is supported by efficacy data.

Ixabepilone

Generic Name: ixabepilone

Brand name: Ixempra

Synonyms: n.a.

What is Ixabepilone?

Xeloda

Generic Name: capecitabine

Brand name: Xeloda

Synonyms: n.a.

What is Xeloda?