Ixazomib Citrate and Ribociclib Succinate

• Generic Name: ixazomib
• Dosage Forms: n.a.
• Other Brand Names: Ninlaro

Used in combination with lenalidomide and dexamethasone for previously treated (≥1 prior therapy) multiple myeloma (designated an orphan drug for this use).

• Generic Name: ribociclib
• Dosage Forms: n.a.
• Other Brand Names: Kisqali

Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.

In combination with an aromatase inhibitor for initial treatment of hormone receptor-positive, human epidermal growth factor receptor type 2 (HER2)-negative advanced or metastatic breast cancer in postmenopausal women.