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Jantoven and Lenalidomide

Determining the interaction of Jantoven and Lenalidomide and the possibility of their joint administration.

Check result:
Jantoven <> Lenalidomide
Relevance: 22.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration of multiple doses of lenalidomide (10 mg/day) with a single dose of warfarin (25 mg) had no effect on the pharmacokinetics of either lenalidomide or R(+) and S(-) warfarin. Expected changes in prothrombin time and INR were observed after warfarin administration, but these changes were not affected by lenalidomide coadministration.

References
  • "Product Information. Revlimid (lenalidomide)." Celgene Corporation, Summit, NJ.
Jantoven

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

Lenalidomide

Generic Name: lenalidomide

Brand name: Revlimid

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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