Janumet XR and Vivitrol

• Generic Name: metformin / sitagliptin
• Dosage Forms: tablet, film coated, extended release
• Other Brand Names: Janumet, Janumet XR

Janumet XR are oral diabetes medicines that help control blood sugar levels.

Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating.

Janumet XR is a combination medicine that is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Janumet XR is not for treating type 1 diabetes.

Janumet XR may also be used for purposes not listed in this medication guide.

• Generic Name: naltrexone
• Dosage Forms: injection
• Other Brand Names: Vivitrol, Depade, ReVia

Vivitrol (naltrexone) blocks the effects of opioid medication, including pain relief or feelings of well-being that can lead to opioid abuse. An opioid is sometimes called a narcotic. Vivitrol is used as part of a treatment program for drug or alcohol dependence.

Vivitrol injection is used to prevent relapse in people who became dependent on opioid medicine and then stopped using it. Naltrexone can help keep you from feeling a "need" to use the opioid.

Vivitrol injection is also used to treat alcoholism by reducing your urge to drink alcohol. This may help you drink less or stop drinking altogether. Naltrexone will not decrease the effects of alcohol you recently consumed. You should not be drinking at the time you receive your first Vivitrol injection.

Naltrexone is not a cure for drug addiction or alcoholism.