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Junel Fe 1.5/30 and Motegrity

Determining the interaction of Junel Fe 1.5/30 and Motegrity and the possibility of their joint administration.

Check result:
Junel Fe 1.5/30 <> Motegrity
Relevance: 06.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Blood levels and effects of oral contraceptives may be reduced if severe diarrhea occurs during treatment with prucalopride. This may increase the risk of breakthrough bleeding and unintended pregnancy. You should use an additional method of birth control if you experience severe diarrhea while taking prucalopride. If diarrhea is persistent, stop taking prucalopride and contact your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADDITIONAL CONTRACEPTION RECOMMENDED: The efficacy of oral contraceptives may be reduced if severe diarrhea occurs with prucalopride treatment. However, prucalopride itself has no clinically significant effect on the pharmacokinetics of oral contraceptives based on data reported for ethinyl estradiol and norethindrone in healthy study subjects.

MANAGEMENT: In patients who develop severe diarrhea during treatment with prucalopride, the use of an additional contraceptive method is recommended to prevent possible failure of oral contraception. If severe or persistent diarrhea occurs, patients should be advised to stop taking prucalopride and consult their physician.

References
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • "Product Information. Resotran (prucalopride)." Janssen Pharmaceuticals, Titusville, NJ.
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Junel Fe 1.5/30

Generic Name: ethinyl estradiol / norethindrone

Brand name: Blisovi 24 Fe, Blisovi Fe 15/30, Blisovi Fe 1/20, Estrostep Fe, Gildess 24 Fe, Gildess Fe 15/30, Gildess Fe 1/20, Junel Fe 15/30, Junel Fe 1/20, Junel Fe 24, Larin 24 Fe, Larin Fe 15/30, Larin Fe 1/20, Lo Loestrin Fe, Loestrin 24 Fe, Loestrin Fe 15/30, Loestrin Fe 1/20, Lomedia 24 Fe, Microgestin 24 Fe, Microgestin Fe 15/30, Microgestin Fe 1/20, Tarina Fe 1/20, Taytulla, Tilia Fe, Tri-Legest Fe, Blisovi 24 Fe, Femcon Fe, Kaitlib FE, Lo Minastrin Fe, Microgestin 24 Fe, Norinyl 1+35, Ortho-Novum 7/7/7, Tri-Norinyl, Zenchent, femhrt 05 mg/25 mcg, Fyavolv, Jevantique Lo, Jinteli, Femcon Fe, Generess FE, Loestrin 1/20, Ovcon 35, Brevicon

Synonyms: n.a.

Motegrity

Generic Name: prucalopride

Brand name: Motegrity

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction