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Juvisync and Lanoxin Pediatric

Determining the interaction of Juvisync and Lanoxin Pediatric and the possibility of their joint administration.

Check result:

Juvisync <> Lanoxin Pediatric

Relevance: 12.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with sitagliptin does not appear to significantly alter the pharmacokinetics of digoxin. Following administration of digoxin 0.25 mg concomitantly with sitagliptin 100 mg daily for 10 days, the peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of digoxin were increased by 18% and 11%, respectively.

References

"Product Information. Januvia (sitagliptin)." Merck & Company Inc, West Point, PA.

Juvisync

Generic Name: simvastatin / sitagliptin

Brand name: Juvisync

Synonyms: n.a.

What is Juvisync?

Lanoxin Pediatric

Generic Name: digoxin

Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin

Synonyms: Lanoxin

What is Lanoxin Pediatric?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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