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Kaletra and Q-Profen

Determining the interaction of Kaletra and Q-Profen and the possibility of their joint administration.

Check result:

Kaletra <> Q-Profen

Relevance: 06.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Ritonavir has a moderate affinity for the CYP450 2C9 microsomal enzyme and may variably affect drugs that are substrates of this enzyme. The area under the plasma concentration-time curves for these drugs may increase or decrease. If concomitant therapy is necessary, close monitoring for therapeutic and adverse effects is strongly recommended. Dosage adjustments should be made as necessary.

References

"Product Information. Norvir (ritonavir)." Abbott Pharmaceutical, Abbott Park, IL.

Kaletra

Generic Name: lopinavir / ritonavir

Brand name: Kaletra

Synonyms: n.a.

What is Kaletra?

Q-Profen

Generic Name: ibuprofen

Brand name: Advil, Advil Liqui-Gels, Midol, Motrin, Motrin IB, Motrin Migraine Pain, Proprinal, Smart Sense Children's Ibuprofen, PediaCare Children’s Pain Reliever/Fever Reducer, PediaCare Infant’s Pain Reliever/Fever Reducer, Caldolor, NeoProfen, Genpril, Ibu, Midol IB, Children's Motrin, Motrin Junior Strength

Synonyms: Q-Profen (Oral)

What is Q-Profen?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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