Kalexate and Lomitapide Mesylate

• Generic Name: sodium polystyrene sulfonate
• Dosage Forms: oral, rectal powder
• Other Brand Names: Kalexate, Kayexalate, Kionex

Kalexate binds itself to potassium in your digestive tract. This helps prevent your body from absorbing too much potassium.

Kalexate is used to treat high levels of potassium in the blood, also called hyperkalemia.

Kalexate works differently from other medicines because it passes into your intestines without being absorbed into your blood stream.

Kalexate may also be used for purposes not listed in this medication guide.

• Generic Name: lomitapide
• Dosage Forms: n.a.
• Other Brand Names: Juxtapid

Adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available, to reduce LDL-cholesterol, total cholesterol, apolipoprotein B (apo B), and non-HDL-cholesterol concentrations in the management of homozygous familial hypercholesterolemia (designated an orphan drug by US FDA for use in this condition).

Safety and efficacy not established in patients with hypercholesterolemia who do not have homozygous familial hypercholesterolemia.

Effects on cardiovascular morbidity and mortality not established.