Kalexate Powder and Krystexxa

• Generic Name: sodium polystyrene sulfonate
• Dosage Forms: oral, rectal powder
• Other Brand Names: Kalexate, Kayexalate, Kionex

Kalexate binds itself to potassium in your digestive tract. This helps prevent your body from absorbing too much potassium.

Kalexate is used to treat high levels of potassium in the blood, also called hyperkalemia.

Kalexate works differently from other medicines because it passes into your intestines without being absorbed into your blood stream.

Kalexate may also be used for purposes not listed in this medication guide.

• Generic Name: pegloticase
• Dosage Forms: injection, solution
• Other Brand Names: Krystexxa

Krystexxa (pegloticase) is an enzyme that metabolizes uric acid into a harmless chemical that is eliminated from the body in urine.

Krystexxa injection is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments.

Krystexxa is usually given after other gout medications have been tried without successful treatment of symptoms.