Kalydeco (Ivacaftor Tablets) and Pantoprazole Sodium

• Generic Name: ivacaftor
• Dosage Forms: tablet, film coated; oral granule
• Other Brand Names: Kalydeco

• It is used to treat cystic fibrosis.

• Generic Name: pantoprazole
• Dosage Forms: n.a.
• Other Brand Names: Protonix, Protonix IV

Orally for short-term treatment of erosive esophagitis in patients with GERD.

Orally to maintain healing and decrease recurrence of erosive esophagitis.

IV for up to 7–10 days in the treatment of GERD in patients with a history of erosive esophagitis. Discontinue IV therapy as soon as patient is able to initiate or resume oral therapy with the drug.

Orally for long-term treatment of pathologic hypersecretory conditions, including Zollinger-Ellison syndrome.

IV for up to 6 days in the treatment of pathologic hypersecretory conditions associated with Zollinger-Ellison syndrome or other neoplastic conditions.

Orally for treatment of duodenal ulcer.

Orally for treatment of gastric ulcer.

Some evidence for use of proton-pump inhibitors (e.g., omeprazole) for gastric acid suppressive therapy as an adjunct in the management of upper GI Crohn’s disease, including esophageal, gastroduodenal, and jejunoileal disease.