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Kapvay and Remeron

Determining the interaction of Kapvay and Remeron and the possibility of their joint administration.

Check result:

Kapvay <> Remeron

Relevance: 24.04.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Mirtazapine may reduce the effects of cloNIDine. You may need a dose adjustment or more frequent monitoring of your blood pressure if you have been taking cloNIDine and are starting treatment with mirtazapine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The antihypertensive effects of clonidine may be antagonized by mirtazapine. The proposed mechanism is opposing effects on adrenergic alpha-2 receptors. A case of hypertensive urgency has been reported. In addition, the risk of CNS-depressant effects may be increased.

MANAGEMENT: If concomitant use cannot be avoided, monitoring for altered efficacy of clonidine is recommended. In some cases, the dosage of clonidine may require upward adjustment.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Abo-Zena RA, Bobek MB, Dweik RA "Hypertensive urgency induced by an interaction of mirtazapine and clonidine." Pharmacotherapy 20 (2000): 476-8

Kapvay

Generic Name: clonidine

Brand name: Catapres, Kapvay, Catapres-TTS, Duraclon, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3

Synonyms: n.a.

What is Kapvay?

Remeron

Generic Name: mirtazapine

Brand name: Remeron, Remeron SolTab

Synonyms: n.a.

What is Remeron?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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