Karbinal ER and Panobinostat Lactate

• Generic Name: carbinoxamine
• Dosage Forms: oral suspension, extended release
• Other Brand Names: Arbinoxa, Karbinal ER, Ryvent, Histex PD, Histex CT, Carbinoxamine PD, Pediox, Histex I/E, Pediatex, Palgic, Histex Pd 12, Carboxine, Cordron NR, Pediatex 12, Mintex PD, Histex PD

Karbinal ER is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Karbinal ER is used to treat runny or stuffy nose, sneezing, itching, watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Karbinal ER may also be used for purposes not listed in this medication guide.

• Generic Name: panobinostat
• Dosage Forms: n.a.
• Other Brand Names: Farydak

In combination with bortezomib and dexamethasone for treatment of multiple myeloma in patients who have received ≥2 prior therapies, including bortezomib and an immunomodulatory agent (designated an orphan drug by FDA for use in this condition ).

Accelerated approval based on progression-free survival; continued approval may be contingent on verification and description of clinical benefit in confirmatory studies.