Kemadrin and Lincomycin Injection

• Generic Name: procyclidine
• Dosage Forms: tablets
• Other Brand Names: Kemadrin

Adjunctive treatment of all forms of parkinsonian syndrome.

May be used as monotherapy for mild to moderate symptoms or in combination with other antiparkinsonian agents for severe symptoms.

Relieves muscle rigidity better than it does tremor; however, tremor, fatigue, weakness, and sluggishness frequently are relieved.

Control of extrapyramidal reactions induced by antipsychotic agents (e.g., phenothiazines).

• Generic Name: lincomycin
• Dosage Forms: injection, solution
• Other Brand Names: Lincocin, Lincorex, L-Mycin, Bactramycin

Treatment of serious infections caused by susceptible staphylococci, Streptococcus pneumoniae, and other streptococci. Because of more potent antibacterial activity, clindamycin usually preferred when a lincosamide antibiotic indicated for treatment of these infections.

Reserve for treatment of serious infections when less toxic alternatives cannot be used (e.g., penicillin-allergic patients or other patients for whom a penicillin is inappropriate). Has been associated with potentially fatal colitis (see Superinfection/Clostridium difficile-associated Diarrhea and Colitis [CDAD] under Cautions); consider nature of the infection and suitability of less toxic alternatives (e.g., erythromycin).

May be used concomitantly with other anti-infectives when indicated.

Certain infections may require incision and drainage or other indicated surgical procedures in addition to anti-infective treatment; use of lincomycin does not eliminate need for surgical procedures when indicated.

Do not use for treatment of meningitis because of inadequate CNS penetration following parenteral administration.