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Ketamine and Succinylcholine Chloride

Determining the interaction of Ketamine and Succinylcholine Chloride and the possibility of their joint administration.

Check result:
Ketamine <> Succinylcholine Chloride
Relevance: 06.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ketamine may increase the effects of succinylcholine, which have led to respiratory depression in some patients. Talk to your doctor if you have any concerns. You should be closely monitored by the doctor during the procedure, and the dosages adjusted as necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Ketamine may potentiate the effects of neuromuscular blockers, including respiratory depression. However, clinical data have been conflicting; both prolonged neuromuscular blockade and no interaction have been reported.

MANAGEMENT: Until more information is available, caution is recommended during concomitant use.

References
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
Ketamine

Generic Name: ketamine

Brand name: Ketalar

Synonyms: n.a.

Succinylcholine Chloride

Generic Name: succinylcholine

Brand name: Anectine, Quelicin

Synonyms: Succinylcholine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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