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Ketamine Injection and Pentothal

Determining the interaction of Ketamine Injection and Pentothal and the possibility of their joint administration.

Check result:
Ketamine Injection <> Pentothal
Relevance: 28.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The hypnotic effect of thiopental may be antagonized by ketamine. The mechanism is unknown. If ketamine and thiopental are used concomitantly, the patient should be monitored for inadequate hypnosis and thiopental dosage should be adjusted as needed.

References
  • Manani G, valenti S, Vincenti E, et al. "Interaction between thiopentone and subhypnotic doses of ketamine." Eur J Anaesthesiol 9 (1992): 43-7
Ketamine Injection

Generic Name: ketamine

Brand name: Ketalar

Synonyms: Ketamine

Pentothal

Generic Name: thiopental

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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