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Ketamine Injection, Concentrate and Quibron-T/SR

Determining the interaction of Ketamine Injection, Concentrate and Quibron-T/SR and the possibility of their joint administration.

Check result:

Ketamine Injection, Concentrate <> Quibron-T/SR

Relevance: 14.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using theophylline together with ketamine may cause seizures. Contact your doctor if you experience confusion, seizures, and other mental status changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Cases of extensor-type seizures have been reported in four asthmatic patients who received aminophylline following induction of anesthesia with ketamine. Causality was not clearly determined due to the presence of other anesthetics. Animal studies suggest that the mechanism of this interaction may involve a lowering of the seizure threshold. Theophylline, dyphylline, and oxtriphylline may also interact.

MANAGEMENT: If aminophylline and ketamine must be used concomitantly, caution should be exercised.

References

Hirshman CA, Krieger W, Littlejohn G, Lee R, Julien R "Ketamine-aminophylline-induced decrease in seizure threshold." Anesthesiology 56 (1982): 464-7

Ketamine Injection, Concentrate

Generic Name: ketamine

Brand name: Ketalar

Synonyms: Ketamine

What is Ketamine Injection, Concentrate?

Quibron-T/SR

Generic Name: theophylline

Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

Synonyms: Quibron-T/SR (Oral), Quibron T/SR

What is Quibron-T/SR?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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