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Ketek Pak and Theo-Time

Determining the interaction of Ketek Pak and Theo-Time and the possibility of their joint administration.

Check result:
Ketek Pak <> Theo-Time
Relevance: 09.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using theophylline together with telithromycin may lead to increased side effects. Telithromycin and theophylline should be taken one hour apart to minimize this interaction. Contact your doctor if you experience nausea and vomiting. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: No clinically relevant pharmacokinetic interaction has been observed with telithromycin and theophylline administered as an extended-release formulation. However, simultaneous administration of theophylline and telithromycin may worsen gastrointestinal side effects such as nausea and vomiting, especially in female patients.

MANAGEMENT: Telithromycin and theophylline should be taken one hour apart to decrease the likelihood of gastrointestinal side effects.

References
  • European Agency for the Evaluation of Medicinal Products. Committee for Proprietary Medicinal Products "European Public Assessment Report Ketek (telithromycin) (Rev. 2) Available from: URL: http:www.emea.eu.int/humandocs/Humans/EPAR/Ketek/Ketek.htm." ([2001]):
  • "Product Information. Ketek (telithromycin)." Aventis Pharmaceuticals, Bridgewater, NJ.
Ketek Pak

Generic Name: telithromycin

Brand name: Ketek

Synonyms: Ketek Pak (Oral)

Theo-Time

Generic Name: theophylline

Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

Synonyms: Theo-Time (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction