Khapzory and Nifedical XL

• Generic Name: levoleucovorin
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Fusilev, Khapzory

Khapzory is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer.

Khapzory is also used to treat or prevent toxic effects of methotrexate in people whose bodies do not eliminate methotrexate properly after the drug is metabolized. This medicine may also be used to treat toxic effects of an overdose or methotrexate or certain other medications.

Khapzory is also used in combination chemotherapy with fluorouracil to treat colorectal cancer that has spread to other parts of the body. This medicine treats only the symptoms of colorectal cancer but does not treat the cancer itself.

Khapzory should not be used to treat anemia that is caused by a lack of vitamin B12.

Khapzory may also be used for purposes not listed in this medication guide.

• Generic Name: nifedipine
• Dosage Forms: tablet, film coated, extended release
• Other Brand Names: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.