Khapzory Injection and Vivitrol

• Generic Name: levoleucovorin
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Fusilev, Khapzory

Khapzory is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer.

Khapzory is also used to treat or prevent toxic effects of methotrexate in people whose bodies do not eliminate methotrexate properly after the drug is metabolized. This medicine may also be used to treat toxic effects of an overdose or methotrexate or certain other medications.

Khapzory is also used in combination chemotherapy with fluorouracil to treat colorectal cancer that has spread to other parts of the body. This medicine treats only the symptoms of colorectal cancer but does not treat the cancer itself.

Khapzory should not be used to treat anemia that is caused by a lack of vitamin B12.

Khapzory may also be used for purposes not listed in this medication guide.

• Generic Name: naltrexone
• Dosage Forms: injection
• Other Brand Names: Vivitrol, Depade, ReVia

Vivitrol (naltrexone) blocks the effects of opioid medication, including pain relief or feelings of well-being that can lead to opioid abuse. An opioid is sometimes called a narcotic. Vivitrol is used as part of a treatment program for drug or alcohol dependence.

Vivitrol injection is used to prevent relapse in people who became dependent on opioid medicine and then stopped using it. Naltrexone can help keep you from feeling a "need" to use the opioid.

Vivitrol injection is also used to treat alcoholism by reducing your urge to drink alcohol. This may help you drink less or stop drinking altogether. Naltrexone will not decrease the effects of alcohol you recently consumed. You should not be drinking at the time you receive your first Vivitrol injection.

Naltrexone is not a cure for drug addiction or alcoholism.