Kineret and Simponi Aria
Determining the interaction of Kineret and Simponi Aria and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using anakinra together with golimumab is not recommended. Combining these medications can increase the risk of serious infections. Contact your doctor immediately if you experience fever, chills, body aches, sore throat, muscle weakness, or other flu-like symptoms during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The use of an interleukin-1 (IL-1) blocker in combination with a tumor necrosis factor (TNF) blocker may increase the risk of neutropenia and serious infections, possibly due to additive immunosuppressive effects. In a clinical study, neutropenia occurred in 3% and serious infections in 7% of patients receiving the IL-1 blocker anakinra in combination with a TNF blocker (n=58). No added benefit has been observed with the combination relative to either agent alone.
MANAGEMENT: Concomitant use of an IL-1 blocker and a TNF blocker is not recommended.
- "Product Information. Cimzia (certolizumab)." UCB Pharma Inc, Smyrna, GA.
- "Product Information. Simponi (golimumab)." Centocor Inc, Malvern, PA.
- "Product Information. Arcalyst (rilonacept)." Regeneron Pharmaceuticals Inc, Tarrytown, NY.
- "Product Information. Ilaris (canakinumab)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. Kineret (anakinra)." Amgen, Thousand Oaks, CA.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: golimumab
Brand name: Simponi Aria, Simponi, Simponi SmartJect
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Kineret-Simuc-HD
- Kineret-Simulect
- Kineret-Simvastatin
- Kineret-Simvastatin and niacin
- Kineret-Simvastatin Oral Suspension
- Kineret-Simvastatin orally disintegrating tablet
- Simponi Aria-Kinlytic
- Simponi Aria-Kinrix
- Simponi Aria-Kionex
- Simponi Aria-Kionex (Sodium Polystyrene Sulfonate Powder)
- Simponi Aria-Kionex (Sodium Polystyrene Sulfonate Suspension)
- Simponi Aria-Kirkland Signature Sleep Aid