Kionex (Sodium Polystyrene Sulfonate Powder) and Meloxicam Suspension
Determining the interaction of Kionex (Sodium Polystyrene Sulfonate Powder) and Meloxicam Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using sodium polystyrene sulfonate together with meloxicam. When sodium polystyrene sulfonate is used with products containing sorbitol, damage to the tissues in the intestine may occur. The condition can be fatal in severe cases. Oral suspensions of some medications may contain sorbitol. If you are taking a liquid preparation of meloxicam or other medication, check the label to be sure it does not contain sorbitol. If you are not sure, ask your doctor or pharmacist. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The concomitant oral or rectal use of sorbitol with polystyrene sulfonate exchange resins may result in colonic necrosis. Fatalities have occurred when uremic patients received sodium polystyrene sulfonate/sorbitol enemas. The mechanism is unknown and causality has not been clearly established. Sorbitol is also present in some oral suspensions (e.g., Mobic, brand of meloxicam).
MANAGEMENT: Until more information is available, the concurrent use of sorbitol as a vehicle or otherwise should generally be avoided in patients receiving polystyrene sulfonate exchange resins.
- "Product Information. Resonium Calcium (calcium polystyrene sulfonate)." Sanofi-Synthelabo Canada Inc, Markham, ON.
- "Product Information. Mobic (meloxicam)" Boehringer-Ingelheim, Ridgefield, CT.
- "Product Information. Kayexalate (sodium polystyrene sulfonate)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Lillemoe KD, Romolo JL, Hamilton SR, Pennington LR, Burdick JF, Williams GM "Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis." Surgery 101 (1987): 267-72
Generic Name: sodium polystyrene sulfonate
Brand name: Kalexate, Kayexalate, Kionex
Synonyms: Kionex
Generic Name: meloxicam
Brand name: Mobic, Vivlodex, Meloxicam Comfort Pac [DSC], Qmiiz ODT
Synonyms: Meloxicam
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Kionex (Sodium Polystyrene Sulfonate Powder)-Melphalan oral/injection
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