Kogenate FS and Selinexor

• Generic Name: antihemophilic factor
• Dosage Forms: injection
• Other Brand Names: Advate, Adynovate, Afstyla, Eloctate with Fc Fusion Protein, Helixate FS, Kogenate FS, Kovaltry, Novoeight, Nuwiq, Recombinate, Xyntha, Hemofil-M, Koate-DVI, Monoclate-P, Jivi, Obizur

Kogenate FS contains recombinant antihemophilic factor. Antihemophilic factor is a naturally occurring protein in the blood that helps blood to clot. A lack of antihemophilic factor VIII is the cause of hemophilia A.

Kogenate FS works by temporarily raising levels of factor VIII in the blood to aid in clotting.

Kogenate FS is used to treat or prevent bleeding episodes in adults and children with hemophilia A. It is also used to control bleeding related to surgery or dentistry in a person with hemophilia, and to prevent joint damage in people age 16 or older with severe hemophilia A and no prior joint damage.

Kogenate FS is not for use in people with von Willebrand disease.

• Generic Name: selinexor
• Dosage Forms: n.a.
• Other Brand Names: Xpovio

Selinexor is used to treat multiple myeloma in adults. Selinexor is given together with a steroid medicine called dexamethasone.

Selinexor is given after other specific medications did not work or have stopped working.

Selinexor was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to selinexor, but further studies are needed.

Selinexor may also be used for purposes not listed in this medication guide.