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Kolephrin and Olopatadine nasal

Determining the interaction of Kolephrin and Olopatadine nasal and the possibility of their joint administration.

Check result:
Kolephrin <> Olopatadine nasal
Relevance: 02.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using olopatadine nasal together with chlorpheniramine may increase side effects such as dizziness, drowsiness, difficulty concentrating, and impaired motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concurrent use of olopatadine nasal spray with alcohol or other central nervous system (CNS) depressants may result in additive impairment of mental alertness and performance. Somnolence has been reported in some patients using olopatadine nasal spray in clinical trials.

MANAGEMENT: Concomitant use of olopatadine nasal spray with alcohol or other CNS depressants should generally be avoided if possible. In the event that they are used together, patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their doctor if they experience excessive or prolonged CNS effects that interfere with their normal activities.

References
  • "Product Information. Patanase (olopatadine nasal)." Alcon Laboratories Inc, Fort Worth, TX.
Kolephrin

Generic Name: acetaminophen / chlorpheniramine / pseudoephedrine

Brand name: Alka-Seltzer Plus Cold Liquigel, Comtrex Allergy Sinus, Comtrex Allergy Sinus Maximum Strength, Kolephrin, Sinutab Ex-Strength, Theraflu Maximum Strength, Singlet, Simplet, Tricom, Theraflu Flu and Cold Medicine Powder, Codimal, Tylenol Gelcap Allergy Sinus, Theraflu Sore Throat Maximum Strength, Allerest Sinus, Tylenol Cold-Child, Tylenol Allergy Sinus Caplet, Tylenol Allergy Sinus Geltab, Comtrex Allergy Sinus Night and Day, Allerest Headache Strength, Sinarest Extra Strength, Sinarest, Children's Tylenol Cold Multi-Symptom, Tylenol Allergy Sinus Gelcap, Children's Tylenol Cold, Triaminicin, Sinutab Maximum Strength Caplets, Sinutab Maximum Strength Non-Drowsy, Actifed Cold & Sinus, Theraflu Cold & Sore Throat, Theraflu Flu & Sore Throat, Allergy Sinus Maximum Strength, Cold Medicine Plus, EQ Cold Plus, Complete Sinus Relief, Sinadrin PE Complete Sinus Relief

Synonyms: n.a.

Olopatadine nasal

Generic Name: olopatadine nasal

Brand name: Patanase

Synonyms: Olopatadine (nasal), Olopatadine (Nasal)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction