Kytril (Granisetron Tablets) and Phenobarbital
Determining the interaction of Kytril (Granisetron Tablets) and Phenobarbital and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:In a human pharmacokinetic study, hepatic enzyme induction with phenobarbital resulted in a 25% increase in total plasma clearance of intravenous granisetron. Given the wide margin of safety of granisetron, the clinical significance of this change is unknown.
- "Product Information. Kytril (granisetron)." SmithKline Beecham, Philadelphia, PA.
Generic Name: granisetron
Brand name: Kytril, Sustol, Sancuso
Synonyms: Kytril
Generic Name: phenobarbital
Brand name: Solfoton, Luminal
Synonyms: PHENobarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Kytril (Granisetron Tablets)-Phenobarbital Elixir
- Kytril (Granisetron Tablets)-Phenobarbital Injection
- Kytril (Granisetron Tablets)-Phenobarbital Oral Solution
- Kytril (Granisetron Tablets)-Phenobarbital Sodium
- Kytril (Granisetron Tablets)-Phenobarbital Sodium Injection
- Kytril (Granisetron Tablets)-Phenobarbital Tablets
- Phenobarbital-Kytril Injection